Efek Kurkumin terhadap Aktivitas Enzim Glutation Peroksidase Mitokondria Hati Tikus

Penulis

  • Syamsudin Syamsudin Universitas Pancasila ,
  • Suyatna FD Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia ,
  • Ganiswarna S Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia ,
  • Sadikin M Bagian Biokimia Fakultas Kedokteran Universitas Indonesia ,

Kata Kunci:

gluthatione peroxidase, t-BHP, Curcumin, mitochondria

Abstrak

This study was conducted to prove the hypothesis that Curcumin could prevent the oxidative damage of rat liver mitochondria induced by t-butylhydroperoxide (t-BHP). The induction of 400 uMt-BHP reduced Gluthatione Peroxidase (GPx) activity from (0.29+0.03) to (0.04+0.01) umol/min/mg protein. Instillation of Curcumin of 1000 uM could elevate GPx activity to (0.16+0.002) umol/min/mg protein.

Referensi

Unduhan

Terbitan

Vol 2 No 2 (2004): JIFI

Bagian

Articles

Lisensi

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