Synthesis and Antioxidant Test of 1,5-bis(3’-etoksi-4’- hidroksifenil)-1,4-pentadien-3-on (EHP) Compound

Authors

  • ESTI MUMPUNI UNIVERSITAS PANCASILA ,
  • ENJANG RUSNAWAN UNIVERSITAS PANCASILA ,
  • EVI SULASTRI UNIVERSITAS PANCASILA ,
  • INDRIANA PERMATASARI UNIVERSITAS PANCASILA ,

Keywords:

1,5-bis(3’-ethoxy-4’-hydroxyphenyl)-1,4-pentadiene-3-on (EHP), antioxidant, synthesis

Abstract

Synthesis of 1,5-bis(3’-etoxy-4’-hydroxyphenyI)-1,4-pentadiene-3-on (EHP) by aldol

condensation method from ethyl Vanilin and acetone, using hydrochloride acid as a catalyst, has been

conducted. Identification of the EHP compound was done through interpretation of UV-Vis, FT-IR,

GC-MS and NMR data, The antioxidant activity of EHP (IC50 8.66 µg/mL) is higher than curcumin (IC50

11.44 µg/mL) as demonstrated by the DPPH method.

References

Downloads

Published

2010-09-30

Issue

Vol. 8 No. 2 (2010): JIFI

Section

Articles

License

Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.

This licence applies to Author(s) and Public Reader means that the users mays :

  • SHARE:
    copy and redistribute the article in any medium or format
  • ADAPT:
    remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication)
  • ALIKE:
    If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original.
  • NO ADDITIONAL RESTRICTIONS:
    You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

It does however mean that when you use it you must:

  • ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

You may not:

  • NONCOMMERCIAL: You may not use the article for commercial purposes.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.