Isolasi, Indentifikasi dan Uji Aktivitas Sitotoksik Skoplatin dari Daun Macaranga hispida(Blume) Mull. Arg

Authors

  • MEGAWATI MEGAWATI UNIVERSITAS INDONESIA ,
  • MUHAMMAD HANAFI Pusat Penelitian Kimia LIPI ,
  • ENDANG SAEPUDIN UNIVERSITAS INDONESIA ,
  • SOFA FAJRIAH Pusat Penelitian Kimia LIPI ,

Keywords:

skopoletin, Macaranga hispida, uji MTT, MCF-7, T47D

Abstract

Skopoletin diisolasi dari ekstrak metanol daun Macaranga hispida. Ekstrak daun diisolasi data spektroskopi dan dibandingkan dengan referensi. Uji sitotoksisitas skopoletin dengan  menggunakan kromatografi dengan pelarut bergradien. Penentuan struktur kimia berdasarkan menggunakan metode assay MTT terhadap sel MCF-7 dan T47D menunjukkan aktivitas sitotoksik yang kuat dengan IC50 51,5 dan 66,5 μg/mL

References

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Published

2017-09-04

Issue

Vol. 14 No. 1 (2016): JIFI

Section

Articles

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