Pengembangan Formulasi Pasta Antiinflamasi Piroksikam Berbasis Ampas Tahu dalam Pemanfaatan Limbah Tahu Di Purwokerto

Authors

  • Nita Triana Sari UNIVERSITAS JENDRAL SOEDIRMAN ,
  • Putri Dewi Riayah UNIVERSITAS JENDRAL SOEDIRMAN ,
  • Nabila Fasya UNIVERSITAS JENDRAL SOEDIRMAN ,
  • Ainul Mardziyati A UNIVERSITAS JENDRAL SOEDIRMAN ,
  • Namira Fadhilah B UNIVERSITAS JENDRAL SOEDIRMAN ,
  • Nuryanti Nuryanti UNIVERSITAS JENDRAL SOEDIRMAN ,

DOI:

https://doi.org/10.35814/jifi.v15i2.505

Keywords:

soybean curd residue, excipient, piroxicam paste

Abstract

The soybean curd residue is the waste product of soybean. It has potential for being excipients in pharmaceutical preparations because of its high carbohydrate element. This study aims to evaluate the soybean curd residue as excipients of piroxicam antiinfl ammatory paste. The excipient of soybean curd residue is made by isolating it with 0.1% KOH, then being characterized by physical, chemical, and functional test after becoming starch. It was prepared in piroxicam antiinfl ammatory paste preparations with ratio of soybean curd residue starch and manihot strach are F1 (0:0.25), F2 (0.25:0), F3 (1.25:1.25), F4 (1.5:1), and F5 (1:1.5). The result of physical and freeze-thaw stability test were analyzed descriptively. The data of viscosity, stickiness, and spreading power test were analyzed using one-way ANOVA. Soybean curd residue starch’s physic is slightly coarse, cubic-shapes powder, uneven surface and nonporous, slightly hygroscopic, and brownish-white. It has distinctive odor and has no taste. Chemical test showed that it contained carbohydrate and had pH 4.9. Functional test showed on average 15% it has viscosity 1959 cps, fl ow time 6.7 seconds and still angle 39.2o. Results of physical and stability tests showed that F3 were the best piroxicam antiinfl ammatory paste formula.

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Published

2017-09-30

Issue

Vol. 15 No. 2 (2017): JIFI

Section

Articles

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