Efek Imunostimulan Ekstrak Etanolik Herba Pegagan (Centella asiatica (L.) Urban) terhadap IgG Mencit Jantan

Authors

  • Shirly Kumala Universitas Pancasila ,
  • Aulia Tisna Dewi Universitas Pancasila ,
  • Yun Astuti Nugroho Badan Penelitian dan Pengembangan Farmasi ,

Keywords:

IgG, Centella asiatica, immunostimulating effect,, sheep red cells

Abstract

The immunostimulating effect of an ethanolic extract of Pegagan herbs to male mice has been determined. Thirty male mice divided into five groups (P1-P5) were induced by 1% sheep red cells for 14 days. P1, P2 and P3 were treated with three doses of an ethanolic extract 4.124 mg/20g BW, 8.25 mg/20g BW and 16.5mg/20gBW respectively. P4 was a positive control using Stimuno 0.55 mg/20g BW, and P5 was a negative control using distilled water Blood samples were taken at day 1, 8 and 15, and the concentration of IgG was measured by Radial Immunodiffusion method. A two way Anova showed no significant difference between P1, P2, and P5, but P3 was higher than P4. The obtained results showed that the ethanolic extract of 16,5 mg has a potent immunostimulating effect.

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Published

2004-09-24

Issue

Vol. 2 No. 2 (2004): JIFI

Section

Articles

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