Isolasi, Indentifikasi dan Uji Aktivitas Sitotoksik Skoplatin dari Daun Macaranga hispida(Blume) Mull. Arg

Penulis

  • MEGAWATI MEGAWATI UNIVERSITAS INDONESIA ,
  • MUHAMMAD HANAFI Pusat Penelitian Kimia LIPI ,
  • ENDANG SAEPUDIN UNIVERSITAS INDONESIA ,
  • SOFA FAJRIAH Pusat Penelitian Kimia LIPI ,

Kata Kunci:

skopoletin, Macaranga hispida, uji MTT, MCF-7, T47D

Abstrak

Scopoletin was isolated from the methanol extract of leaves of Macaranga hispida. leaf extract was isolated using chromatography with a solvent gradient. Determination of chemical structurebased on spectroscopic data and compared with the reference. Scopoletin cytotoxicity test using MTT assay method against MCF-7 and T47D cells showed strong cytotoxic activity with IC50 of 51.5 and 66.5μg /mL.

Referensi

Diterbitkan

2017-09-04

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