Standardization of the Extract of Cultivated Ipomoea reptans Poir. Leaves from Sardonoharjo, Sleman and Its Potency as Antioxidant

Penulis

  • FARIDA HAYATI UNIVERSITAS ISLAM INDONESIA ,
  • ARI WIBOWO UNIVERSITAS ISLAM INDONESIA ,
  • PINUS JUMARYATNO UNIVERSITAS ISLAM INDONESIA ,
  • ARDE TOGA NUGROHO UNIVERSITAS ISLAM INDONESIA ,
  • DIAN AMALIA UNIVERSITAS ISLAM INDONESIA ,

Kata Kunci:

Standardisasi, kangkung, ekstrak, parameter spesifik, parameter nonspesifik

Abstrak

Standardization of the extract is conducted to assure the uniformity of the efficacy and to improve the quality of the herbal medicine. The aims of this study were to determine the values of specific and nonspecific parameter of the standardized extract of cultivated Ipomoea reptans Poir. leaves from Sardonoharjo, Sleman, DIY. The Ipomoea reptans Poir was harvested at the age of ± 25-30 days. Extraction was performed by maceration method using ethanol 96%. Specific parameters include the organoleptic tests, chromatography profile, concentration of the marker compound. The result showed that the standardized extract of cultivated Ipomoea reptans Poir. leaves from Sardonoharjo, Sleman, DIY has moisture content value of 16.45 ±0.05% with the density of the extract was 3.26±3.37x10-3 g/mL and the total ash value of 4.52± 0.77%. There was no ethanol residue detected in the extract. Furthermore, the values of microbial contamination, mold and yeast contamination, coliform contamination and metal contamination such as Pb and Cd in the extract were below the maximum standard of BPOM. Based on the chromatogram evaluation using TLC-densitometry, the concentration value of β-karoten in the extract was 5.7 % w/w. The IC50 value of extract was 178.3 μg/ mL.

Referensi

Unduhan

Diterbitkan

2017-09-23

Terbitan

Vol 13 No 2 (2015): JIFI

Bagian

Articles

Lisensi

Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.

This licence applies to Author(s) and Public Reader means that the users mays :

  • SHARE:
    copy and redistribute the article in any medium or format
  • ADAPT:
    remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication)
  • ALIKE:
    If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original.
  • NO ADDITIONAL RESTRICTIONS:
    You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

It does however mean that when you use it you must:

  • ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

You may not:

  • NONCOMMERCIAL: You may not use the article for commercial purposes.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.