Red Rosella Calyx Extract Prevent the Increase of Malondialdehyde of Wistar Rats Exposed to Cigarette Smoke

Penulis

  • ARYA ULILALBAB STIKES Karya Husada ,
  • BAMBANG WIRJATMADI UNIVERSITAS AIRLANGGA ,
  • MERRYANA ADRIANI UNIVERSITAS AIRLANGGA ,

Kata Kunci:

MDA serum, rosella merah, antioksidan, asap rokok, radikal bebas

Abstrak

Currently, the number of smokers in Indonesia are still high. Cigarette smoke contains free
radicals. This study was aimed to analyze the effects of red rosella extract on the prevention of the
increaseing of malondialdehyde (MDA) serum of wistar rats exposed to cigarette smoke. The total
sample of 20 male rats were divided into four groups: negative control, positive control, treatment of red
rosella calyx extract dose 270 mg/bw and red rosella calyx extract dose 540 mg/bw. Negative control
only given with standard feed. Positive control given by standard feed + exposed to 2 cigarettes a day.
Treatment group were feeded by standard + red rosella calyx extract in the morning and exposed to 2
cigarettes after that. This study was conducted for 28 days. At the end of the study, blood serum was
analyzed to determine MDA. The results of the study of MDA serum test was analyzed with One Way
ANOVA and followed by Tukey HSD test at 5% level. The giving of red rosella calyx extract dose 270
mg/bw and red rosella calyx extract dose 540 mg/bw can significantly prevent the increase of MDA
serum in wistar rats exposed to cigarette smoke.

Referensi

Unduhan

Diterbitkan

2017-09-23

Terbitan

Vol 13 No 2 (2015): JIFI

Bagian

Articles

Lisensi

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